VU0360172
VU0360172 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 5 (mGlu5), with an EC50 of 16 nM and a Ki of 195 nM. This research compound is widely used in vitro and in vivo to investigate mGlu5's role in central nervous system functions, including synaptic plasticity and related disorders.
Product Specifications
CAS Number
1310012-12-4
Product Name Alternative
PI hydrolysis, Polyphosphoinositide, VU0360172, VU-0360172, VU 0360172, Metabotropic glutamate receptors, mGluR, mGlu5, inhibit, Inhibitor, CD1 mice
Field of Research
Neuroscience
Purity
99.56% (May vary between batches)
Solubility
DMSO:83 mg/mL (282.01 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (11.21 mM)
Smiles
Fc1cccc (c1) C#Cc1ccc (cn1) C (=O) NC1CCC1
Molecular Formula
C18H15FN2O
Molecular Weight
294.32
Storage Conditions
-20°C
Notes
For research use only.
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