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VU0360172

VU0360172 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 5 (mGlu5), with an EC50 of 16 nM and a Ki of 195 nM. This research compound is widely used in vitro and in vivo to investigate mGlu5's role in central nervous system functions, including synaptic plasticity and related disorders.

Product Specifications

CAS Number

1310012-12-4

Product Name Alternative

PI hydrolysis, Polyphosphoinositide, VU0360172, VU-0360172, VU 0360172, Metabotropic glutamate receptors, mGluR, mGlu5, inhibit, Inhibitor, CD1 mice

Field of Research

Neuroscience

Purity

99.56% (May vary between batches)

Solubility

DMSO:83 mg/mL (282.01 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (11.21 mM)

Smiles

Fc1cccc (c1) C#Cc1ccc (cn1) C (=O) NC1CCC1

Molecular Formula

C18H15FN2O

Molecular Weight

294.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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