Phloretin
Phloretin (NSC-407292) is a natural dihydrochalcone and a potent inhibitor of eukaryotic urea transporters, notably blocking VacA-mediated transport. It exhibits strong antioxidative properties and has demonstrated in vitro efficacy in inhibiting proliferation and inducing apoptosis in various cancer cell lines, including B16 melanoma and HL60 leukemia cells.
Product Specifications
CAS Number
60-82-2
Product Name Alternative
Dihydronaringenin, NSC407292, NSC-407292, NSC 407292, inhibit, Inhibitor, EndogenousMetabolite, Endogenous Metabolite, GLUT, Glucose transporter, Sodium-dependent glucose cotransporters, RJC 02792, RJC02792, RJC-02792, Phloretin, SGLT1, SGLT, SGLT2
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.53% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.03 mM) ; Ethanol:48 mg/mL (175.01 mM) ; DMSO:80 mg/mL (291.68 mM)
Smiles
C (CCC1=CC=C (O) C=C1) (=O) C2=C (O) C=C (O) C=C2O
Molecular Formula
C15H14O5
Molecular Weight
274.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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