VE-821
VE-821 is a potent and selective ATP-competitive inhibitor of the ATR kinase, with a Ki of 13 nM and an IC50 of 26 nM in biochemical assays. It is widely used in preclinical research to study DNA damage response pathways, demonstrating chemosensitizing effects in various cancer cell lines and in vivo tumor models.
Product Specifications
CAS Number
1232410-49-9
Product Name Alternative
ATR, ATR Inhibitor IV, ATM/ATR, ATM and RAD3 related, ATM, Ataxia telangiectasia mutated, inhibit, Inhibitor, VE 821, VE821, VE-821
Field of Research
Molecular Biology, Signal Transduction
Purity
>98%
Bioactivity
ATR inhibitor
Form
Powder
Solubility
Soluble in DMSO (40 mg/ml)
Smiles
CS (=O) (=O) c1ccc (cc1) -c1cnc (N) c (n1) C (=O) Nc1ccccc1
Molecular Formula
C18H16N4O3S
Molecular Weight
368.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3-Amino-6-[4- (methlsulfonyl) phenyl) -N-phenyl-2-pyrazinecarboxamide
Available Sizes
Frequently Asked Questions
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