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JAK2 Inhibitor V

JAK2 Inhibitor V is a potent and selective small molecule that dose-dependently suppresses the autophosphorylation of both wild-type JAK2 and the V617F mutant. This inhibitor is a valuable research tool for studying JAK2-driven pathologies, such as myeloproliferative neoplasms, in both cellular and animal models.

Product Specifications

CAS Number

195371-52-9

Product Name Alternative

Z3, Z-3, Z 3, JAK, JAK2, JAK2 Inhibitor V Z3, JAK2 (V617F), JAK2 Inhibitor V, NSC42834, NSC-42834, NSC 42834

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Purity

95.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.81 mM) ; DMSO:60 mg/mL (174.19 mM)

Smiles

CC (CCc1ccccn1) (CCc1ccccn1) C (=O) c1ccccc1

Molecular Formula

C23H24N2O

Molecular Weight

344.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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