Salubrinal
Salubrinal is a selective phosphatase inhibitor (IC50=1.7 μM against PP1) that protects phosphorylated eukaryotic initiation factor 2α (eIF2α) . This activity makes it a valuable research tool for studying cellular stress responses, protein synthesis regulation, and ER stress in both in vitro and in vivo models.
Product Specifications
CAS Number
405060-95-9
Product Name Alternative
Apoptosis, Autophagy, inhibit, Inhibitor, Herpes simplex virus, eIF-2α, HSV, Phosphatase, Salubrinal
Field of Research
Cell Biology
Purity
>98%
Bioactivity
EIF2α Phosphatase inhibitor; ER stress inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
ClC (Cl) (Cl) C (NC (=S) NC1=CC=CC2=CC=CN=C12) NC (=O) \C=C\C1=CC=CC=C1
Molecular Formula
C21 H17 Cl3 N4 O S
Molecular Weight
479.81
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3-Phenyl-N-[2,2,2-trichloro-1-[[ (8-quinolinylamino) thioxomethyl]amino]ethyl]-2-propenamide
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