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ML-7 hydrochloride

ML-7 hydrochloride is a cell-permeable, ATP-competitive inhibitor of myosin light chain kinase (MLCK) with a Ki of 300 nM. It is used in vitro and in vivo to investigate cytoskeletal regulation, smooth muscle contraction, and endothelial barrier function in cardiovascular and cell migration studies.

Product Specifications

CAS Number

110448-33-4

Product Name Alternative

ML-7 HCl, ML7 hydrochloride, ML7 Hydrochloride, ML-7 Hydrochloride, MLCK, ML7, ML-7, ML 7, ML 7 hydrochloride, ML 7 Hydrochloride, Inhibitor, inhibit, Myosin, threoninkinase, Serinekinase, threonin kinase, Serine kinase, PKA, PKC, Yes-associated protein, YAP

Field of Research

Cell Biology, Epigenetics & Chromatin, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.00% (May vary between batches)

Solubility

DMSO:46 mg/mL (101.6 mM)

Smiles

Cl.Ic1cccc2c (cccc12) S (=O) (=O) N1CCCNCC1

Molecular Formula

C15H18ClIN2O2S

Molecular Weight

452.74

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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