SMI-4a
(Z) -SMI-4a, also known as TCS PIM-1 4a, is a potent and selective ATP-competitive inhibitor targeting Pim-1 kinase, exhibiting an IC50 value of 21 nM. This compound is a valuable research tool for investigating Pim-1's role in oncology and hematology, with utility in both cellular and biochemical studies.
Product Specifications
CAS Number
438190-29-5
Product Name Alternative
Cell-permeable, 4E-BP1, (Z) SMI4a, (Z) SMI 4a, Pim-2, Pim, Pim1, Pim-1, SMI-4a, TCS PIM-1 4a
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
>98%
Bioactivity
PIM1 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 40 mg/ml with warming) .
Smiles
FC (F) (F) C1=CC=CC (\C=C2\SC (=O) NC2=O) =C1
Molecular Formula
C11H6F3NO2S
Molecular Weight
273.23
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5- (3-Trifluoromethylbenzylidene) thiazolidine
Available Sizes
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