ALK-IN-1
ALK-IN-1 is a synthetic small molecule inhibitor of anaplastic lymphoma kinase (ALK), structurally related to Brigatinib. It is utilized in biochemical and cellular research to investigate ALK-driven signaling pathways and has been employed in both in vitro and in vivo studies to explore potential anti-tumor mechanisms.
Product Specifications
CAS Number
1197958-12-5
Product Name Alternative
EGFR (C797S/del19), EGFR (del19), IGF1R, IGF-1R, AP 26113, AP26113, AP-26113, AP26113-analog, AP26113-analog, Anaplastic lymphoma kinase, Anaplastic lymphoma kinase (ALK), ALKIN1, ALK-IN-1, ALK, ALK tyrosine kinase receptor, ALK IN 1, Cluster of differentiation 246, CD246, Brigatinib, Brigatinib-analog
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.66% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:98 mg/mL (185.25 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.78 mM) ; DMSO:30 mg/mL (56.71 mM)
Smiles
N (C1=C (P (C) (C) =O) C=CC=C1) C2=NC (NC3=C (OC) C=C (C=C3) N4CCC (N (C) C) CC4) =NC=C2Cl
Molecular Formula
C26H34ClN6O2P
Molecular Weight
529.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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