XL019
XL019 is a highly selective small molecule inhibitor of JAK2, exhibiting potent activity with an IC50 of 2.2 nM and demonstrating 100-fold selectivity against JAK1. It is a valuable research tool for studying JAK2-dependent signaling in cellular assays and has been utilized in preclinical models of myeloproliferative neoplasms.
Product Specifications
CAS Number
945755-56-6
Product Name Alternative
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.19% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.5 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:13 mg/mL (29.24 mM)
Smiles
O=C (Nc1ccc (cc1) -c1ccnc (Nc2ccc (cc2) N2CCOCC2) n1) [C@@H]1CCCN1
Molecular Formula
C25H28N6O2
Molecular Weight
444.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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