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Carotegrast methyl

Carotegrast methyl (AJM300) is an orally bioavailable small molecule antagonist that selectively targets both α4β1 and α4β7 integrins. It is a research tool for investigating integrin function in inflammatory and autoimmune diseases, with demonstrated utility in both in vitro adhesion assays and in vivo models of colitis.

Product Specifications

CAS Number

401905-67-7

Product Name Alternative

AJM 300, AJM300, AJM-300, Carotegrast methyl, colitis, Inhibitor, Integrin, HCA2969, inhibit, Jurkat, orally, TK-1, RPMI-8866, α4β1 integrin

Field of Research

Signal Transduction

Purity

98.73% (May vary between batches)

Solubility

DMSO:100 mg/mL (175.61 mM)

Smiles

COC (=O) [C@H] (Cc1ccc (cc1) -n1c (=O) n (C) c2ccc (cc2c1=O) N (C) C) NC (=O) c1c (Cl) cccc1Cl

Molecular Formula

C28H26Cl2N4O5

Molecular Weight

569.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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