GLPG0634 analog
GLPG0634 analog is a selective JAK1 inhibitor, exhibiting IC50 values of 10, 28, 810, and 116 nM against JAK1, JAK2, JAK3, and TYK2, respectively. This compound is a valuable research tool for investigating JAK-STAT pathway biology in both cellular and animal models of autoimmune and inflammatory diseases.
Product Specifications
CAS Number
1206101-20-3
Product Name Alternative
AK-STAT, Inhibitor, inhibit, Janus kinase, JAK3, JAK2, JAK, JAK1, OSM/IL-lβ, Hela cell, GLPG0634 analog, GLPG-0634 analog, GLPG0634 analogue, GLPG 0634, GLPG0634, GLPG-0634, TYK2, TyrosineKinases, Tyrosine Kinases
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.62% (May vary between batches)
Solubility
DMSO:7.5 mg/mL (18.27 mM)
Smiles
O=C (Nc1nc2cccc (-c3ccc (OCc4ccc (nc4) C#N) cc3) n2n1) C1CC1
Molecular Formula
C23H18N6O2
Molecular Weight
410.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6461714-01 0.1 mL
ADIPOR1, CT (Adiponectin Receptor Protein 1, Progestin And adipoQ Receptor Family Member I, CGI-45, PAQR1, TESBP1A) (MaxLight 490)
Sign In for Pricing
View Details 
MBS6461714-02 5x 0.1 mL
ADIPOR1, CT (Adiponectin Receptor Protein 1, Progestin And adipoQ Receptor Family Member I, CGI-45, PAQR1, TESBP1A) (MaxLight 490)
Sign In for Pricing
View Details 10291-TA-500 500 µg
Recombinant Human TNF-alpha (HEK293-expressed) Protein CF
Sign In for Pricing
View Details EIA06052m 1 Kit
Mouse Macrophage Inflammatory Protein 1 Alpha (MIP-1α) ELISA kit
Sign In for Pricing
View Details LH08518V 100 µg
TATA Element Modulatory Factor 1 (TMF1) (NM_007114) Human Over-expression Lysate
Sign In for Pricing
View Details