SGI-1776
SGI-1776 is a Pim kinase inhibitor investigated in preclinical and clinical research for hematological and solid tumors. Studies have explored its application in prostate cancer, non-Hodgkin's lymphoma, and relapsed/refractory leukemias, demonstrating activity in both in vitro and in vivo models.
Product Specifications
CAS Number
1025065-69-3
Product Name Alternative
Pim, Pim1, Pim3, Pim2, Pim-Kinase Inhibitor IX, SGI 1776, SGI1776, SGI-1776, SGI-1776 free base, Autophagy, Apoptosis, FLT3
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
99.03% (May vary between batches)
Solubility
Ethanol:75 mg/mL (184.99 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (6.17 mM) ; DMSO:52 mg/mL (128.26 mM)
Smiles
CN1CCC (CNc2ccc3ncc (-c4cccc (OC (F) (F) F) c4) n3n2) CC1
Molecular Formula
C20H22F3N5O
Molecular Weight
405.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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