What is the catalog number for SGC0946?

The catalog number for SGC0946 is orb1304559.

What sizes are available for SGC0946?

SGC0946 is available in the following size(s): 2 mg, 5 mg, 1 ml x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg.

How many pack sizes does SGC0946 come in?

SGC0946 is available in 6 different pack sizes.

SGC0946 is currently made to order / not held in immediate stock. Contact us for lead time.

SGC0946

SGC0946 is a potent and selective DOT1L methyltransferase inhibitor with an IC50 of 0.3 nM. It induces selective cell death in MLL-rearranged leukemia cells and is a valuable chemical probe for studying histone methylation in both in vitro and in vivo cancer research models.

Product Specifications

CAS Number

1561178-17-3

Product Name Alternative

TOV21G, SGC 0946, SGC0946, SGC-0946, cord blood cells, DOT1L, HistoneMethyltransferase, Histone Methyltransferase, Inhibitor, leukemia, ovarian cancer, Molm13 MLL, MLL-rearrange, inhibit

Field of Research

Epigenetics & Chromatin

Purity

98.00% (May vary between batches)

Solubility

Ethanol:93 mg/mL (150.35 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.33 mM) ; DMSO:150 mg/mL (242.49 mM)