N-Ethylmaleimide
N-Ethylmaleimide (NEM) is a small molecule alkylating agent that covalently modifies cysteine residues. It is widely used in biochemical research as an inhibitor of cysteine proteases, deubiquitinating enzymes, and mitochondrial phosphate transport in both in vitro and cell-based studies.
Product Specifications
CAS Number
128-53-0
Product Name Alternative
1-Ethyl-1H-pyrrole-2,5-dione, Cathepsin, Apoptosis, DUBs, Deubiquitinase, Cysteine protease, cysteine residue, CysteineProtease, Cysteine Protease, NEM, NEthylmaleimide, N-Ethylmaleimide, modify, N Ethylmaleimide, inhibit, Inhibitor, Ethylmaleimide, sulfhydryl, phosphate transport, VSMC
Field of Research
Protein Biochemistry
Purity
>98%
Bioactivity
Cysteine protease inhibitor
Form
Powder
Solubility
DMSO:237.5 mg/mL (1898.03 mM) ;5% DMSO+95% Saline:1.2 mg/mL (9.59 mM) ; H2O:50 mg/mL (399.58 mM)
Smiles
C (C) N1C (=O) C=CC1=O
Molecular Formula
C6H7NO2
Molecular Weight
125.13
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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