Nigericin Na
Nigericin sodium salt is a cationic ionophore antibiotic that activates the NLRP3 inflammasome and exhibits antibacterial activity against Gram-positive bacteria. It is widely used in research to study inflammasome biology, pyroptosis, and cellular ion transport in both cellular and animal models.
Product Specifications
CAS Number
28643-80-3
Product Name Alternative
Antibiotic K178; Antibiotic X-464; Azalomycin M; PolyetherinA
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Induces rapid intracellular acidification
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 20 mg/ml) .
Smiles
[Na+].[H][C@@]1 (C[C@H] (C) [C@@] ([H]) (O1) [C@]1 (C) CC[C@@] ([H]) (O1) [C@]1 (C) C[C@@H] (C) [C@]2 (O1) O[C@] ([H]) (C[C@@]1 ([H]) CC[C@H] (C) [C@@] ([H]) (O1) [C@@H] (C) C ([O-]) =O) C[C@@H] (OC) [C@H]2C) [C@@]1 ([H]) O[C@@] (O) (CO) [C@H] (C) C[C@@H]1C
Molecular Formula
C40H57O11Na
Molecular Weight
746.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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