NQDI-1
NQDI-1 is a selective, cell-permeable inhibitor of apoptosis signal-regulating kinase 1 (ASK1/MAP3K5) with an IC50 of 3 μM. It is a valuable research tool for studying ASK1's role in oxidative stress, apoptosis, and inflammatory pathways in both cellular and animal models of related diseases.
Product Specifications
CAS Number
175026-96-7
Product Name Alternative
Apoptosis, ASK1, Inhibitor, MAP3K, MAP3K5, MAP kinase kinase kinase, MEKK, MAPKKK, NQDI 1, NQDI1, NQDI-1, inhibit
Field of Research
Cell Biology, Neuroscience, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
ASK1 inhibitor
Form
Powder
Solubility
Soluble in DMSO (3 mg/ml)
Smiles
CCOC (=O) c1c2-c3ccccc3C (=O) c3cccc ([nH]c1=O) c23
Molecular Formula
C19H13NO4
Molecular Weight
319.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2,7-dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid, ethyl ester
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