CUDC-101
CUDC-101 is a multi-targeted small molecule inhibitor with potent activity against HDAC, EGFR, and HER2, exhibiting IC50 values of 4.4 nM, 2.4 nM, and 15.7 nM, respectively. It has been investigated in preclinical cancer research for its potential to overcome resistance and has shown efficacy in both cellular and animal models of various solid tumors.
Product Specifications
CAS Number
1012054-59-9
Product Name Alternative
CUDC 101, CUDC101, CUDC-101, HDAC1, HDAC3, HDAC2, HDAC4, HDAC10, HDAC8, HDAC5, HDAC, HDAC7, HDAC9, HDAC6, HER2, HER1, Histone deacetylases, Epidermal growth factor receptor, ErbB-1, EGFR, Inhibitor, inhibit
Field of Research
Epigenetics & Chromatin
Purity
>98%
Bioactivity
Dual HDAC and EGFR inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
N (C=1C2=C (C=C (OC) C (OCCCCCCC (NO) =O) =C2) N=CN1) C3=CC (C#C) =CC=C3
Molecular Formula
C24H26N4O4
Molecular Weight
434.49
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
7- ((4- ((3-Ethynylphenyl) amino) -7-methoxyquinazolin-6-yl) oxy) -N-hydroxyheptanamide
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV639585 1.0 µg DNA
Zfp597 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
Sign In for Pricing
View Details 
bs-0778R-BF750-TR 20 µL
CD90/Thy-1 Polyclonal Antibody, AbBy Fluor™ 750 Conjugated
Sign In for Pricing
View Details 
MBS1274732-01 0.01 mg Plasmid + 0.2 mL Glycerol-Stock
SPN cDNA Clone
Sign In for Pricing
View Details MBS1274732-02 5x 0.01 mg Plasmid + 5x 0.2 mL Glycerol-Stock
SPN cDNA Clone
Sign In for Pricing
View Details