PRT-4165
PRT4165 (NSC600157) is a small molecule inhibitor that potently and selectively blocks PRC1-mediated H2A ubiquitination. It is a valuable chemical probe for studying epigenetic regulation in cancer and stem cell biology, with utility in both in vitro biochemical assays and cellular research.
Product Specifications
CAS Number
31083-55-3
Product Name Alternative
E3Enzyme, E3 ligating enzyme, E2Enzyme, E3 Enzyme, E1/E2/E3 Enzyme, E1Enzyme, E2 Enzyme, E2 conjugating enzyme, E1 Enzyme, E1 activating enzyme, BMI1, BMI-1, inhibit, NSC 600157, NSC600157, NSC-600157, Inhibitor, Ring1A, PRT 4165, PRT4165, PRT-4165, Ubiquitin activating enzyme, Ubiquitin ligase, Ubiquitin conjugating enzyme
Field of Research
Protein Biochemistry
Purity
>98%
Bioactivity
E3 Ubiquitin ligase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 6 mg/ml with warming) .
Smiles
O=C1C (=Cc2cccnc2) C (=O) c2ccccc12
Molecular Formula
C15H9NO2
Molecular Weight
235.24
Storage Conditions
RT
Notes
For research use only.
Other Product Names
2- (3-Pyridinylmethylene) -1H-indene-1,3 (2H) -dione
Available Sizes
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