CRT0273750
CRT0273750 is a potent autotaxin (ATX) inhibitor with an IC50 of 14 nM, effectively modulating lysophosphatidic acid (LPA) levels. This small molecule is a valuable research tool for investigating the ATX-LPA axis in oncology, fibrosis, and inflammation, suitable for both in vitro biochemical assays and in vivo pharmacological studies.
Product Specifications
CAS Number
1979939-16-6
Product Name Alternative
CRT 0273750, CRT-0273750, CRT0273750, clearance, blood, ATX (autotaxin), ATX/LPA, 4T1, LPA, inhibit, Inhibitor
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.49% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (6.56 mM) ; DMSO:200 mg/mL (397.68 mM)
Smiles
C[C@H] (NC (=O) CCc1nc2cccnc2n1Cc1ccc (OC (F) (F) F) cc1) c1ccc (Cl) cc1
Molecular Formula
C25H22ClF3N4O2
Molecular Weight
502.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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