What is the catalog number for Abemaciclib?

The catalog number for Abemaciclib is orb1304526.

What sizes are available for Abemaciclib?

Abemaciclib is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does Abemaciclib come in?

Abemaciclib is available in 2 different pack sizes.

Is Abemaciclib in stock?

Abemaciclib is currently made to order / not held in immediate stock. Contact us for lead time.

Abemaciclib

Abemaciclib methanesulfonate (LY2835219) is a potent and selective inhibitor of CDK4 (IC50=2 nM) and CDK6 (IC50=10 nM) . It is widely used in cancer research, demonstrating activity in both in vitro cell proliferation assays and in vivo xenograft models for studying cell cycle progression and oncology therapeutics.

Product Specifications

CAS Number

1231930-82-7

Product Name Alternative

LY2835219 mesylate

Field of Research

Cell Biology

Purity

>98%

Bioactivity

CDK 4/6 inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to at least 25 mg/ml)

Smiles

CS (O) (=O) =O.CCN1CCN (Cc2ccc (Nc3ncc (F) c (n3) -c3cc (F) c4nc (C) n (C (C) C) c4c3) nc2) CC1

Molecular Formula

C27H32F2N8·CH3SO3H

Molecular Weight

602.70

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

N-[5-[ (4-Ethylpiperazin-1-yl) methyl]pyridine-2-yl]-5-fluoro-4- (7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl) pyrimidin-2-amine methanesulfonic acid salt