Verteporfin
Verteporfin is a clinically used photosensitizer and a small molecule inhibitor of the YAP-TEAD protein interaction, a key pathway in the Hippo signaling cascade. It has been widely utilized in research to study oncogenesis, fibrosis, and regenerative processes, demonstrating effects on apoptosis and autophagy in both cellular and animal models.
Product Specifications
CAS Number
129497-78-5
Product Name Alternative
CL 318,952; BPD-MA
Field of Research
Cardiovascular Research, Cell Biology, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
YAP inhibitor; Anticancer activity
Form
Powder
Solubility
Soluble in DMSO (up to 14 mg/ml)
Smiles
COC (=O) CCc1c (C) c2cc3[nH]c (cc4nc (cc5[nH]c (cc1n2) c (CCC (O) =O) c5C) [C@]1 (C) [C@H] (C (=O) OC) C (=CC=C41) C (=O) OC) c (C) c3C=C
Molecular Formula
C41H42N4O8
Molecular Weight
718.8
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(4R,4aS) -18-Ethenyl-4,4a-dihydro-3,4-bis (methoxycarbonyl) -4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester
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