KM11060
KM11060 is a small molecule corrector that addresses the F508del-CFTR trafficking defect, enhancing the delivery and functional expression of the CFTR channel at the cell surface. It is a research tool used in vitro to study cystic fibrosis pathophysiology and the rescue mechanisms of mutant CFTR.
Product Specifications
CAS Number
774549-97-2
Product Name Alternative
CFTR, Cystic fibrosis transmembrane conductance regulator, Autophagy, inhibit, KM 11060, KM11060, KM-11060, Inhibitor
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.86% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:4 mg/mL (9.47 mM) ; DMSO:42.2 mg/mL (99.92 mM)
Smiles
Clc1ccc (cc1) S (=O) (=O) N1CCN (CC1) c1ccnc2cc (Cl) ccc12
Molecular Formula
C19H17Cl2N3O2S
Molecular Weight
422.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TP721451 10 µg
SLC2A12 Human Recombinant Protein, Synthetic Nanodisc
Sign In for Pricing
View Details 
24154116 3x 1.0 µg
Icos sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
Sign In for Pricing
View Details 172050-AF-ML750 100 µL
CD45 (B220, CD45R, GP180, Leukocyte common antigen, LCA, Loc, Ly-5, Lyt-4, Protein tyrosine phosphatase receptor type C, PTPRC, Receptor-type tyrosine-Protein phosphatase C, T200 GlycoProtein) (BSA & Azide Free) (MaxLight 750) discontinued
Sign In for Pricing
View Details