KM11060
KM11060 is a small molecule corrector that addresses the F508del-CFTR trafficking defect, enhancing the delivery and functional expression of the CFTR channel at the cell surface. It is a research tool used in vitro to study cystic fibrosis pathophysiology and the rescue mechanisms of mutant CFTR.
Product Specifications
CAS Number
774549-97-2
Product Name Alternative
CFTR, Cystic fibrosis transmembrane conductance regulator, Autophagy, inhibit, KM 11060, KM11060, KM-11060, Inhibitor
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.86% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:4 mg/mL (9.47 mM) ; DMSO:42.2 mg/mL (99.92 mM)
Smiles
Clc1ccc (cc1) S (=O) (=O) N1CCN (CC1) c1ccnc2cc (Cl) ccc12
Molecular Formula
C19H17Cl2N3O2S
Molecular Weight
422.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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