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KM11060

KM11060 is a small molecule corrector that addresses the F508del-CFTR trafficking defect, enhancing the delivery and functional expression of the CFTR channel at the cell surface. It is a research tool used in vitro to study cystic fibrosis pathophysiology and the rescue mechanisms of mutant CFTR.

Product Specifications

CAS Number

774549-97-2

Product Name Alternative

CFTR, Cystic fibrosis transmembrane conductance regulator, Autophagy, inhibit, KM 11060, KM11060, KM-11060, Inhibitor

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Purity

98.86% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:4 mg/mL (9.47 mM) ; DMSO:42.2 mg/mL (99.92 mM)

Smiles

Clc1ccc (cc1) S (=O) (=O) N1CCN (CC1) c1ccnc2cc (Cl) ccc12

Molecular Formula

C19H17Cl2N3O2S

Molecular Weight

422.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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