DY268
DY268 is a potent and selective FXR antagonist with an IC50 of 7.5 nM, derived from a trisubstituted pyrazolamide scaffold. It exhibits no FXR agonist activity or cytotoxicity, making it a valuable research tool for investigating FXR-related pathways in metabolic and liver diseases during in vitro and in vivo studies.
Product Specifications
CAS Number
1609564-75-1
Product Name Alternative
DY 268, DY268, DY-268, FXR, Inhibitor, inhibit, NR1H4
Field of Research
Metabolism Research
Purity
98.48% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.92 mM) ; DMSO:50 mg/mL (89.18 mM) ; H2O:Insoluble
Smiles
C (NC1=CC (S (=O) (=O) N2CCOCC2) =C (C) C=C1) (=O) C=3C (=NN (CC4=CC (OC) =CC=C4) C3) C5=CC=C (C) C=C5
Molecular Formula
C30H32N4O5S
Molecular Weight
560.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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