MN-64
MN-64 is a potent and selective tankyrase 1 inhibitor (IC50 = 6 nM) that effectively suppresses Wnt/β-catenin signaling. This small molecule is a valuable chemical probe for studying Wnt-driven pathologies, including cancer, in both cellular and animal models.
Product Specifications
CAS Number
92831-11-3
Product Name Alternative
Betacatenin, beta-catenin, bcatenin, inhibit, PARP, MN64, MN-64, MN 64, Inhibitor, βcatenin, Tankyrase, TNKS1, TNKS2, Wnt/betacatenin, Wnt/b-catenin, Wnt, Wnt/β-catenin, poly ADP ribose polymerase
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.36% (May vary between batches)
Solubility
DMSO:12 mg/mL (45.4 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.57 mM)
Smiles
CC (C) c1ccc (cc1) -c1cc (=O) c2ccccc2o1
Molecular Formula
C18H16O2
Molecular Weight
264.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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