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Orexin 2 Receptor Agonist

This small molecule OX2R agonist exhibits potent and selective activation of the orexin 2 receptor (EC50 = 23 nM), with a 70-fold selectivity over OX1R. It is a valuable research tool for studying orexin signaling in sleep/wake regulation, metabolism, and reward processing in both cellular and animal models.

Product Specifications

CAS Number

1796565-52-0

Product Name Alternative

HCRT Receptor, Hypocretin Receptor, Inhibitor, O2XR, inhibit, Orexin Receptor (OX Receptor), Orexin 2 Receptor Agonist, OX Receptor, OX2R, OXReceptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.26% (May vary between batches)

Solubility

DMSO:50 mg/mL (85.22 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.41 mM)

Smiles

S (NC1=CC (NCCNC (=O) C2=CC (C) =CC=C2) =CC=C1) (=O) (=O) C=3C=C (C=CC3OC) C4=CC (C (N (C) C) =O) =CC=C4

Molecular Formula

C32H34N4O5S

Molecular Weight

586.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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