Pimelic diphenylamide 106
RGFA-8 (Pimelic diphenylamide 106) is a potent and selective slow, tight-binding inhibitor of Class I HDAC enzymes, demonstrating nanomolar IC50 values against HDAC1, 2, and 3. This compound is a valuable chemical probe for epigenetic research, facilitating the study of histone deacetylation in both cellular and biochemical assays.
Product Specifications
CAS Number
937039-45-7
Product Name Alternative
Inhibitor, HDAC, Histone Deacetylase Inhibitor VII, Histone deacetylases, inhibit, RGFA 8, RGFA8, RGFA-8, TC-H 106, TC-H106, TC-H-106, Pimelic diphenylamide 106, Pimelic Diphenylamide106, Pimelic Diphenylamide-106
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Purity
95.25% (May vary between batches)
Solubility
DMSO:55 mg/mL (162.04 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.95 mM)
Smiles
Cc1ccc (NC (=O) CCCCCC (=O) Nc2ccccc2N) cc1
Molecular Formula
C20H25N3O2
Molecular Weight
339.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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