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Tanshinone IIA sulfonate sodium

Tanshinone IIA sulfonate sodium is a water-soluble derivative of Salvia miltiorrhiza and a potent negative allosteric modulator of the human P2X7 receptor. It has demonstrated research utility in models of pulmonary hypertension, where it inhibits hypoxia-induced downregulation of PKG and PPAR-γ in rat PASMCs and pulmonary arteries.

Product Specifications

CAS Number

69659-80-9

Product Name Alternative

Calcium Channel, Calcium release-activated channels, Ca2+ release-activated Ca2+ channels, CaMK, CYP3A4, CRAC Channel, CalciumChannel, Sodium Tanshinone IIA sulfonate, Tanshinone IIA sodium sulfonate, Tanshinone IIA sulfonate, Tanshinone IIA sulfonate sodium

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Purity

97.95% (May vary between batches)

Solubility

10% DMSO+90% Saline:2.5 mg/mL (6.31 mM) ; DMSO:85 mg/mL (214.44 mM)

Smiles

[Na+].Cc1c2c (oc1S ([O-]) (=O) =O) -c1ccc3c (CCCC3 (C) C) c1C (=O) C2=O

Molecular Formula

C19H17O6S·Na

Molecular Weight

396.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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