Tanshinone IIA sulfonate sodium
Tanshinone IIA sulfonate sodium is a water-soluble derivative of Salvia miltiorrhiza and a potent negative allosteric modulator of the human P2X7 receptor. It has demonstrated research utility in models of pulmonary hypertension, where it inhibits hypoxia-induced downregulation of PKG and PPAR-γ in rat PASMCs and pulmonary arteries.
Product Specifications
CAS Number
69659-80-9
Product Name Alternative
Calcium Channel, Calcium release-activated channels, Ca2+ release-activated Ca2+ channels, CaMK, CYP3A4, CRAC Channel, CalciumChannel, Sodium Tanshinone IIA sulfonate, Tanshinone IIA sodium sulfonate, Tanshinone IIA sulfonate, Tanshinone IIA sulfonate sodium
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
97.95% (May vary between batches)
Solubility
10% DMSO+90% Saline:2.5 mg/mL (6.31 mM) ; DMSO:85 mg/mL (214.44 mM)
Smiles
[Na+].Cc1c2c (oc1S ([O-]) (=O) =O) -c1ccc3c (CCCC3 (C) C) c1C (=O) C2=O
Molecular Formula
C19H17O6S·Na
Molecular Weight
396.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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