Indole-3-carbinol
Indole-3-carbinol (I3C) is a natural, orally bioavailable compound derived from glucobrassicanin. It functions as an inhibitor of NF-κB signaling by blocking IκBα kinase activation. This small molecule is widely used in research areas such as cancer, inflammation, and immunology for both in vitro and in vivo experimental studies.
Product Specifications
CAS Number
700-06-1
Product Name Alternative
Inhibitor, I3C, EndogenousMetabolite, Indole 3 carbinol, Indole3carbinol, Indole-3-carbinol, Indole-3-Methanol, inhibit, p53, Nuclear factor-kappaB, Nuclear factor-κB, NF-κB, NFκB, NFkB, NF-kB, 3-Indolemethanol, AhR, ArylHydrocarbonReceptor, Aryl Hydrocarbon Receptor, E1 activating enzyme, E1 Enzyme, E2 Enzyme, E2 conjugating enzyme, E1Enzyme, E1/E2/E3 Enzyme, Endogenous Metabolite, E3 ligating enzyme, E3Enzyme, E3 Enzyme, E2Enzyme, Ubiquitin conjugating enzyme, Ubiquitin ligase, Ubiquitin activating enzyme
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction
Purity
97.06% (May vary between batches)
Solubility
DMSO:1.61 mg/mL (10.94 mM) ; Ethanol:28 mg/mL (190.26 mM) ; H2O:7 mg/mL (47.56 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (6.79 mM)
Smiles
C (O) C=1C=2C (NC1) =CC=CC2
Molecular Formula
C9H9NO
Molecular Weight
147.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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