Aleplasinin
Aleplasinin (PAZ 417) is an orally bioavailable, selective inhibitor of plasminogen activator inhibitor-1 (PAI-1), a primary regulator of fibrinolysis. Its application in research includes in vitro enzymatic assays and in vivo models for studying Alzheimer's disease pathology and other conditions involving impaired fibrinolytic activity.
Product Specifications
CAS Number
481629-87-2
Product Name Alternative
BBB-penetrated, Amyloid-β, Aleplasinin, Alzheimer's disease, Abeta, PAZ 417, PAZ417, PAZ-417, PAI1, PAI-1, inhibit, memory deficiency, Inhibitor, Plasminogen activator inhibitor-1, orally active, Serpin family, β-amyloid peptide
Field of Research
Metabolism Research, Neuroscience
Purity
97.51% (May vary between batches)
Solubility
DMSO:245 mg/mL (575.77 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.75 mM)
Smiles
Cc1cccc (c1) -c1ccc2n (Cc3ccc (cc3) C (C) (C) C) cc (C (=O) C (O) =O) c2c1
Molecular Formula
C28H27NO3
Molecular Weight
425.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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