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Voacamine

Voacamine (Voacanginine) is an indole alkaloid with dual activity as a cannabinoid CB1 receptor antagonist and a P-glycoprotein (P-gp) inhibitor. Its potential rhythmic effects and ability to overcome multidrug resistance in tumor cells make it a compound of interest for neuropharmacology and oncology research, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

3371-85-5

Product Name Alternative

Inhibitor, inhibit, Multidrug resistance protein 1, obesity, metabolic, MDR1, alkaloid, ABCB1, cannabinoid, Cannabinoid Receptor, CannabinoidReceptor, antagonistic, Cluster of differentiation 243, CD243, CB, CB1, syndrome, P-glycoprotein, Pgp, P-gp, P-gp (P-glycoprotein), receptor, Voacamine, Voacanginine

Field of Research

Cardiovascular Research, Cell Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.54% (May vary between batches)

Solubility

DMSO:7.05 mg/mL (10 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.42 mM)

Smiles

CC[C@H]1C[C@H]2CN3CCc4c ([nH]c5cc ([C@H]6C[C@@H]7C ([C@@H] (Cc8c6[nH]c6ccccc86) N (C) C\C7=C\C) C (=O) OC) c (OC) cc45) [C@] (C2) ([C@H]13) C (=O) OC

Molecular Formula

C43H52N4O5

Molecular Weight

704.9

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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