6-Hydroxycoumarin
6-Hydroxycoumarin is a small molecule inhibitor of carbonic anhydrases CA9 and CA12. It demonstrates cytotoxic activity in vitro against human cancer cell lines, including HL60, HCT116, and COLO205, with IC50 values ranging from 35 to 42 μM. This compound is used in biochemical research to study tumor metabolism and hypoxia-related pathways.
Product Specifications
CAS Number
6093-68-1
Product Name Alternative
Inhibit, Inhibitor, CA12, CA9, 6 Hydroxycoumarin, 6-hydroxychromen-2-one, 6Hydroxycoumarin, 6-Hydroxycoumarin, Carbonic Anhydrase, CarbonicAnhydrase
Field of Research
Infectious Disease & Virology, Metabolism Research
Purity
98.50% (May vary between batches)
Solubility
DMSO:20 mg/mL (123.35 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (30.84 mM)
Smiles
Oc1ccc2oc (=O) ccc2c1
Molecular Formula
C9H6O3
Molecular Weight
162.14
Storage Conditions
-20°C
Notes
For research use only.
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