Polyethylene glycol mono (4-tert-octylphenyl) ether surfactant

Polyethylene glycol mono (4-tert-octylphenyl) ether surfactant is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono (4-tert-octylphenyl) ether surfactant is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono (4-tert-octylphenyl) ether surfactant is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono (4-tert-octylphenyl) ether surfactant is a nonionic surfactant. Polyethylene glycol mono (4-tert-octylphenyl) ether surfactant induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV[1][2][3][4][5].

Product Specifications

CAS Number

[9002-93-1]

UNSPSC

12352200

Hazard Statement

H302, H315, H318, H410

Target

Apoptosis; Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Apoptosis; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/polyethylene-glycol-mono-4-octylphenyl-ether.html

Purity

99.20

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)(C)CC(C)(C)C1=CC=C(OCCO)C=C1.[n]

Precautions

H302, H315, H318, H410

References & Citations

[1]Colavita F, et al.Evaluation of the inactivation effect of Triton X-100 on Ebola virus infectivity. J Clin Virol. 2017 Jan;86:27-30. |[2]Herman SM, et al. The hidden allergen: Triton X-100, a derivative of polyethylene glycol. J Allergy Clin Immunol Pract. 2021 Jul;9 (7) :2941. |[3]Koley D, et al. Triton X-100 concentration effects on membrane permeability of a single HeLa cell by scanning electrochemical microscopy (SECM) . Proc Natl Acad Sci U S A. 2010 Sep 28;107 (39) :16783-7. |[4]Ghosh R, et al. Unraveling diverse action of triton X-100 and methimazole on lysozyme fibrillation/aggregation: Physicochemical insights. Int J Biol Macromol. 2021 Jan 15;167:736-745. |[5]Borner MM, et al. The detergent Triton X-100 induces a death pattern in human carcinoma cell lines that resembles cytotoxic lymphocyte-induced apoptosis. FEBS Lett. 1994 Oct 17;353 (2) :129-32.