Negletein
Negletein (7-O-Methylbaicalein) is a multi-functional flavonoid with demonstrated bioactivity in research models. It exhibits neuroprotective, anti-inflammatory, and antioxidant properties, activating Nrf2 and inhibiting NFAT. Studies show it induces neurite outgrowth in PC12 cells, protects against hypoxia in vivo, and inhibits amyloid-beta oligomerization in vitro.
Product Specifications
CAS Number
29550-13-8
Product Name Alternative
7-O-Methylbaicalein, anti-inflammatory, Baicalein-7-methylether, cell, nerve, Negletein, neurite, neuroprotectant, outgrowth, PC12, ILReceptor, IL-1β, inhibit, IL Receptor, Inhibitor, iNOS, Interleukin, Interleukin Related, growth, factor, TNF-α, TNF Receptor, TNFR, Tumor Necrosis Factor Receptor
Field of Research
Cell Biology, Immunology & Inflammation
Purity
98.00% (May vary between batches)
Solubility
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble; DMSO:50 mg/mL (175.9 mM)
Smiles
COc1cc2oc (cc (=O) c2c (O) c1O) -c1ccccc1
Molecular Formula
C16H12O5
Molecular Weight
284.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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