BFH772
BFH772 is a potent and selective small-molecule VEGF inhibitor, structurally analogous to BAW2881. It primarily targets VEGFR2 kinase with high potency (IC50 = 3 nM) and also inhibits RET, PDGFR, and KIT autophosphorylation. This profile supports its research use in angiogenesis, oncology, and related in vitro and in vivo studies.
Product Specifications
CAS Number
890128-81-1
Product Name Alternative
BFH 722, BFH 772, BFH722, BFH-722, BFH772, BFH-772, Inhibitor, inhibit, VEGFR2, VEGFR, Vascular endothelial growth factor receptor
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.71% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (7.51 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:81 mg/mL (184.35 mM) ; DMSO:81 mg/mL (184.35 mM)
Smiles
OCc1cc (Oc2ccc3c (cccc3c2) C (=O) Nc2cccc (c2) C (F) (F) F) ncn1
Molecular Formula
C23H16F3N3O3
Molecular Weight
439.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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