Sodium dichloroacetate
Sodium dichloroacetate (DCA) is a small molecule PDK inhibitor that shifts tumor cell metabolism from glycolysis to oxidative phosphorylation. This action reduces lactate, elevates ROS, and induces apoptosis, making it a valuable tool for studying cancer metabolism in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2156-56-1
Product Name Alternative
ReactiveOxygenSpecies, Reactive Oxygen Species, Sodium Dichloroacetate, Sodium bichloroacetic acid, Sodium dichloroacetate, Sodium dichloroacetate (DCA), dehydrogenase, DCA sodium salt, DCA, BCA, bichloroacetic acid, Apoptosis, NKCC, PDK, PDH kinase, PDH, PDHK, pyruvate, Pyruvate dehydrogenase kinase, mitochondria, lactic
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.17% (May vary between batches)
Solubility
H2O:166.66 mg/mL (1104.29 mM) ; DMSO:26 mg/mL (172.28 mM)
Smiles
C (C (=O) [O-]) (Cl) Cl.[Na+]
Molecular Formula
C2HCl2NaO2
Molecular Weight
150.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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