DS-7423
DS-7423 is a potent dual inhibitor targeting both PI3Kα and mTOR with nanomolar IC50 values, while showing lower potency against other class I PI3K isoforms. This small molecule is used in preclinical research to investigate PI3K/mTOR pathway signaling in cancer models, both in vitro and in vivo.
Product Specifications
CAS Number
1222104-37-1
Product Name Alternative
TP53, TP53AIP1, PUMA, PI3Kα, PI3K, Phosphoinositide 3-kinase, DS7423, DS-7423, DS 7423, Mammalian target of Rapamycin, Inhibitor, mTOR, inhibit, OCCC
Field of Research
Signal Transduction
Purity
99.68% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.84 mM) ; DMSO:65 mg/mL (124.88 mM)
Smiles
C[C@@H]1CN (CCN1C (C) =O) c1nc2c (nc (nc2n1CC (F) (F) F) -c1cnc (N) nc1) N1CCOCC1
Molecular Formula
C22H27F3N10O2
Molecular Weight
520.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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