Solcitinib
Solcitinib (GLPG-0778, GSK2586184) is a selective JAK1 inhibitor investigated for autoimmune conditions like psoriasis, ulcerative colitis, and lupus. Preclinical in vitro and in vivo studies have demonstrated its potential to modulate cytokine signaling pathways relevant to these inflammatory diseases.
Product Specifications
CAS Number
1206163-45-2
Product Name Alternative
Solcitinib, Inhibitor, GLPG 0778, GLPG0778, GLPG-0778, GSK 2586184, GSK2586184, GSK-2586184, inhibit, Janus kinase, JAK, JAK1
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.25% (May vary between batches)
Solubility
DMSO:10 mg/mL (25.68 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.57 mM)
Smiles
CC1 (C) CN (C1) C (=O) c1ccc (cc1) -c1cccc2nc (NC (=O) C3CC3) nn12
Molecular Formula
C22H23N5O2
Molecular Weight
389.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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