CP-640186 hydrochloride
CP-640186 hydrochloride is a potent, non-selective inhibitor of acetyl-CoA carboxylase (ACC) isoforms, demonstrating IC50 values of 53 nM for rat ACC1 and 61 nM for rat ACC2. This compound exhibits enhanced metabolic stability and is a valuable tool for investigating lipid metabolism in both cellular and animal models of metabolic diseases.
Product Specifications
CAS Number
591778-70-0
Product Name Alternative
ACC, AcetylCoA Carboxylase, Acetyl-CoA Carboxylase, AcetylCoACarboxylase, ACC2, ACC1, ACC, Acetyl Coenzyme A Carboxylase, C2C12, CP640186, CP-640186, CP640186 hydrochloride, CP640186 Hydrochloride, CP-640186 Hydrochloride, CP 640186, CP 640186 HCl, CP 640186 Hydrochloride, CP 640186 hydrochloride, inhibit, muscle strips, muscle fatty acid oxidation, H460, human fibroblasts, Inhibitor, HepG2
Field of Research
Metabolism Research
Purity
98.86% (May vary between batches)
Solubility
DMSO:50 mg/mL (95.77 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.83 mM)
Smiles
Cl.O=C ([C@@H]1CCCN (C1) C1CCN (CC1) C (=O) c1c2ccccc2cc2ccccc12) N1CCOCC1
Molecular Formula
C30H36ClN3O3
Molecular Weight
522.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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