PF-8380
PF-8380 is a potent, orally bioavailable autotaxin inhibitor that effectively lowers lysophosphatidic acid (LPA) levels in vitro and in vivo. It is widely used in research on fibrosis, cancer, and inflammatory diseases, demonstrating efficacy in reducing LPA at inflammation sites in experimental models.
Product Specifications
CAS Number
1144035-53-9
Product Name Alternative
Autotaxin, inhibit, Inhibitor, PF 8380, PF8380, PF-8380, phosphodiesterase, Phosphodiesterase (PDE)
Field of Research
Metabolism Research
Purity
98.70% (May vary between batches)
Solubility
DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Clc1cc (Cl) cc (COC (=O) N2CCN (CCC (=O) c3ccc4[nH]c (=O) oc4c3) CC2) c1
Molecular Formula
C22H21Cl2N3O5
Molecular Weight
478.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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