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PF-8380

PF-8380 is a potent, orally bioavailable autotaxin inhibitor that effectively lowers lysophosphatidic acid (LPA) levels in vitro and in vivo. It is widely used in research on fibrosis, cancer, and inflammatory diseases, demonstrating efficacy in reducing LPA at inflammation sites in experimental models.

Product Specifications

CAS Number

1144035-53-9

Product Name Alternative

Autotaxin, inhibit, Inhibitor, PF 8380, PF8380, PF-8380, phosphodiesterase, Phosphodiesterase (PDE)

Field of Research

Metabolism Research

Purity

98.70% (May vary between batches)

Solubility

DMSO:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Clc1cc (Cl) cc (COC (=O) N2CCN (CCC (=O) c3ccc4[nH]c (=O) oc4c3) CC2) c1

Molecular Formula

C22H21Cl2N3O5

Molecular Weight

478.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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