What is the catalog number for (E) -SIS3?

The catalog number for (E) -SIS3 is orb1303973.

What sizes are available for (E) -SIS3?

(E) -SIS3 is available in the following size(s): 1 mg, 2 mg, 5 mg, 1 ml x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 500 mg.

How many pack sizes does (E) -SIS3 come in?

(E) -SIS3 is available in 9 different pack sizes.

Is (E) -SIS3 in stock?

(E) -SIS3 is currently made to order / not held in immediate stock. Contact us for lead time.

(E) -SIS3

(E) -SIS3 is a selective small molecule inhibitor of Smad3 with an IC50 of 3 μM. It effectively blocks TGF-β1-induced fibroblast-to-myofibroblast differentiation, making it a valuable research tool for studying fibrotic diseases in both cellular and animal models.

Product Specifications

CAS Number

521984-48-5

Product Name Alternative

(E) SIS3, (E) SIS3, (E) -SIS3, (E) -SIS-3, Smad3, Smad, SIS 3, SIS3, SIS-3, SIS3 HCl, SIS3 hydrobromide, TGFβ, TGF-β/Smad, TGFbeta, TGF-beta, TGF-beta/Smad, TGFbeta/Smad, TGF-b/Smad, TGFb, Transforming growth factor beta

Field of Research

Stem Cell & Developmental Biology

Purity

95.64% (May vary between batches)

Solubility

Ethanol:23 mg/mL (46.94 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:100 mg/mL (204.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.73 mM)