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A-804598

A-804598 is a potent and selective competitive antagonist of the P2X7 receptor, demonstrating low nanomolar IC50 values across rat, mouse, and human variants. It is a valuable research tool for investigating the role of P2X7 in neuroinflammation, pain, and immune responses in both cellular and animal models.

Product Specifications

CAS Number

1125758-85-1

Product Name Alternative

Inhibitor, inhibit, A 804598, A804598, A-804598, P2XReceptor, P2XRs, P2X7, P2X Receptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.57% (May vary between batches)

Solubility

DMSO:31.5 mg/mL (99.88 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.34 mM)

Smiles

C[C@H] (N (C (=N) NC#N) c1cccc2ncccc12) c1ccccc1

Molecular Formula

C19H17N5

Molecular Weight

315.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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