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YM-58483

YM-58483 (BTP2) is a potent and selective CRAC channel inhibitor that effectively suppresses store-operated calcium entry (SOCE) and downstream calcium signaling. This tool compound is widely used in both in vitro and in vivo research to investigate immune cell activation, T-cell proliferation, and mast cell degranulation.

Product Specifications

CAS Number

223499-30-7

Product Name Alternative

BTP2

Field of Research

Immunology & Inflammation

Purity

>98%

Bioactivity

CRAC channel blocker

Form

Powder

Solubility

Soluble in DMSO (up to 40 mg/ml)

Smiles

Cc1nnsc1C (=O) Nc1ccc (cc1) -n1nc (cc1C (F) (F) F) C (F) (F) F

Molecular Formula

C15H9F6N5OS

Molecular Weight

421.3

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

N-[4-[3,5-Bis (trifluoromethyl) -1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide

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