YM-58483
YM-58483 (BTP2) is a potent and selective CRAC channel inhibitor that effectively suppresses store-operated calcium entry (SOCE) and downstream calcium signaling. This tool compound is widely used in both in vitro and in vivo research to investigate immune cell activation, T-cell proliferation, and mast cell degranulation.
Product Specifications
CAS Number
223499-30-7
Product Name Alternative
BTP2
Field of Research
Immunology & Inflammation
Purity
>98%
Bioactivity
CRAC channel blocker
Form
Powder
Solubility
Soluble in DMSO (up to 40 mg/ml)
Smiles
Cc1nnsc1C (=O) Nc1ccc (cc1) -n1nc (cc1C (F) (F) F) C (F) (F) F
Molecular Formula
C15H9F6N5OS
Molecular Weight
421.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[4-[3,5-Bis (trifluoromethyl) -1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide
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