COR659
COR659 is a 2-acylaminothiophene derivative that functions as a GABAB receptor positive allosteric modulator and a cannabinoid CB1 receptor antagonist/inverse agonist. It has been shown to reduce alcohol and chocolate self-administration in rodent models, supporting its use in preclinical research on addiction and reward-related behaviors.
Product Specifications
CAS Number
544450-68-2
Product Name Alternative
COR659, COR-659, COR 659, chocolate, CB1, Cannabinoid Receptor, CannabinoidReceptor, alcohol, GABA Receptor, GABAReceptor, GABAB, Gamma-aminobutyric acid Receptor, Inhibitor, inhibit, sucrose, γ-Aminobutyric acid Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.56% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.92 mM) ; DMSO:33.33 mg/mL (98.66 mM)
Smiles
CCc1c (C) sc (NC (=O) c2ccc (Cl) cc2) c1C (=O) OC
Molecular Formula
C16H16ClNO3S
Molecular Weight
337.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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