Citarinostat
ACY-241 (Citarinostat) is a selective, orally bioavailable HDAC inhibitor with antineoplastic potential. It induces histone hyperacetylation and gene expression changes, leading to cell cycle arrest and apoptosis in tumor cells. Research applications include in vitro cytotoxicity studies and in vivo models for multiple myeloma and solid tumors.
Product Specifications
CAS Number
1316215-12-9
Product Name Alternative
Citarinostat, combination, anti-proliferation, anticancer, ACY241, ACY-241, ACY 241, Histone deacetylases, HDAC3, HDAC6, HDAC2, HDAC1, HDAC, HDAC-IN-2, HDAC8, Inhibitor, inhibit, multiple. myeloma, α-tubulin
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
97.94% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.27 mM) ; DMSO:37 mg/mL (79.07 mM)
Smiles
ONC (=O) CCCCCCNC (=O) c1cnc (nc1) N (c1ccccc1) c1ccccc1Cl
Molecular Formula
C24H26ClN5O3
Molecular Weight
467.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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